学术论坛报告 ——Prof. Deyu Li:Mapping Brain Activity with Single Synapse Resolution

发布者:发布时间:2015-12-24浏览次数:1102

 本期学术论坛由Vanderbilt University的Prof.Deyu Li主讲


题目:Mapping Brain Activity with Single Synapse Resolution

报告人:Prof.Deyu Li

时间:20151225下午 2:00

地点:机械学院南高厅

  

报告摘要:

Our amazing brain, the most complex and dynamic network found in nature, is composed of billions of neurons with trillions of dendritic spines and synapses.  Interestingly, individual spines and synapses are unique and display different electrical properties, posing a daunting challenge to neurotechnology for mapping brain activity with single-synapse resolution to understand how these fundamental neural network building blocks behave to achieve higher brain function.  In response to this challenge, we are creating a novel graphene optoelectronic probes to measure the activity of individual spines and synapses throughout complex neuronal networks.  We culture neuronal networks and whole retina using graphene-based microfluidic platforms and using scanning photocurrent microscopy to scan large areas of neural networks with single synapse resolution.  I will discuss the demonstrated ultrahigh spatiotemporal resolution of this powerful neurotechnology, which could lead to an in-depth understanding of cognitive behavior and new therapeutic approaches for treating neuronal and psychiatric disorders.

In addition, I will discuss a few more projects on-going in my research group, including biomechanics and mechanobiology of normal and cancer associated fibroblasts, as well as some recent progress in understanding thermal transport through nanowires with fine structures.


  

报告人简介:

Dr. Deyu Li received his B.S., M.E., and Ph.D. degrees from the University of Science and Technology of China, Tsinghua University, and the University of California, Berkeley, respectively.  He joined Vanderbilt University in 2004 as an assistant professor in the Department of Mechanical Engineering, was promoted to associate professor in 2010, and has been approved for full professor promotion effective July 1st, 2016.  His research interest includes nanoscale thermal transport and micro/nanofluidics.  He has published 67 journal papers, which have been cited over 4200 times according to Web of Science.  He received an NSF career award in 2007, Vanderbilt Chancellor’s Award for Research in 2013, and his research has also won best poster awards in MRS and IMECE.


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据院有关规定:

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